Evils lords that aren't the 3,6, or 11

For some lagnas, bphs gives evil planets that are not the 3, 6, or 11 lords.

Should we then consider these to be yoga breakers as well, or at least disruptors?

E.g., for Libra ascendant, Saturn in the 4th forms yoga by himself, but then suppose he is opposite Mars, the 2nd and 7th lord that bphs says is also evil...so then I should subtract Mars's inauspicious value from Saturn's auspicious value to determine the strenght of the yoga?